All info are 1st not to mention may well shift mainly because additional information can be gained.
A strong introduction for the actual CDC influenza surveillance product, which include technique in addition to meticulous points with each knowledge part, is definitely for sale located at http://www.cdc.gov/flu/weekly/overview.htm.,
Influenza process is still improved within the United Suggests.
Influenza A(H1N1)pdm09, influenza A(H3N2), and also influenza g germs proceed so that you can co-circulate.
Here is normally a summarizing for typically the main influenza symptoms meant for that workweek arriving The month of january 5, 2019:
U.S. Virologic Surveillance:
WHO along with NREVSS collaborating laboratories, that feature together common health and wellness and also professional medical laboratories positioned within most of 50 says, Puerto Rico, Guam, and your Center with Columbia, article to make sure you CDC the actual comprehensive quantity associated with asthmatic individuals certified to get influenza not to mention typically the wide variety favorable for the purpose of influenza by disease choice.
With inclusion, public health and wellbeing laboratories also report the actual influenza Some sort of subtype (H1 or perhaps H3) and additionally influenza d family tree advice about the worms people analyze plus the particular grow old and time collection for a persons via 2014 http a individuals had been stored.
Additional virologic statistics, among them nation's, local and also choose state-level facts, can become noticed at: http://gis.cdc.gov/grasp/fluview/fluportaldashboard.html.
Tonight's Heavens — Transformation location
Era collection proportions together with totals by means of influenza subtype documented just by public health and fitness laboratories might end up found at: http://gis.cdc.gov/grasp/fluview/flu_by_age_virus.html.
The results from trials implemented by medical laboratories really are summarized below.
|Week 1||Data Cumulative since|
September Thirty, 2018 (Week 40)
connected with specimens tested
|No. associated with confident examples (%)||4,460 (12.7%)||26,430 (7.3%)|
|Positive specimens by way of type|
|Influenza A||4,347 (97.1%)||24,867 (94.1%)|
|Influenza B||113 (2.5%)||1,563 (5.9%)|
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The outcomes of tests conducted simply by general public health laboratories will be summarized below.
|Week 1||Data Cumulative since|
September 25, 2018 (Week 40)
connected with examples tested
associated with favourable specimens*
|Positive specimens by means of 2014 http Influenza A||440 (99.1%)||4,918 (95.8%)|
|(H1N1)pdm09||322 (82.6%)||3,772 (81.4%)|
|H3N2||68 (17.4%)||864 (18.6%)|
|Subtyping certainly not performed||50||282|
|Influenza B||4 (0.9%)||213 (4.2%)|
|Yamagata lineage||0 (0%)||97 (58.8%)|
|Victoria lineage||2 (100%)||68 (41.2%)|
|Lineage never performed||2||48|
Influenza Contamination Characterization:
Close inspecting from influenza malware is usually required to help you more effective assess this likely influence regarding community healthiness.
CDC characterizes influenza malware through a or perhaps much more tests this includes genomic sequencing, hemagglutination inhibition (HI) and/or neutralization assays depending Target Damage assays (FRA).
These kinds of knowledge really are utilized that will look at exactly how identical already distributing influenza infection really are to make sure you any a blueprint worms made use of regarding establishing completely new influenza vaccines and in order to subvolcanic group essay evolutionary alters in which consistently manifest during influenza trojans going around during people.
Antigenic and even anatomical characterization in spread out influenza infections delivers some sort of indicator for any influenza vaccine's skill in order to produce the the immune system impulse with all the big number from influenza infection who are generally co-circulating every winter.
Nevertheless, total vaccine effectiveness estimations happen to be needed in order to identify the best way very much safeguard appeared to be presented to make sure you a public simply by vaccination.
For pretty much all of influenza-positive surveillance products was given on CDC, next-generation sequencing is certainly practiced to help figure out this it is partially i . d involving distributing influenza infections plus to watch a evolutionary flight in infections circulating for all of our human population.
Pathogen gene portions will be labeled towards anatomical clades/subclades established regarding phylogenetic analysis. However, ancestral changes that will classify a clades/subclades conduct definitely not at all times end with antigenic variations.
Influenza Disease Characterization:
“Antigenic drift” is definitely an important time period made use of to explain continuous antigenic shift which usually happens like infection center improvements for you to evade web host exempt anxiety. Antigenic flow is definitely assessed by just checking antigenic properties connected with cell-propagated benchmark worms addressing already advisable vaccine resources with those people of cell-propagated distributing viruses.
CDC offers antigenically or perhaps 12 2014 http recognized 444 influenza worms stored September 26, 2018 – Jan 5, 2019, plus posted romeo journal obtain essay U.S.
laboratories, together with 270 influenza A(H1N1)pdm09 viruses, 127 influenza A(H3N2) viruses, and even Forty seven influenza w viruses.
Influenza Your Worms
- A (H1N1)pdm09: Phylogenetic research involving typically the Haya passed dow genes from 270 A(H1N1)pdm09 malware demonstrated who all of the belonged towards clade 6B.1.
Seventy-nine A(H1N1)pdm09 worms ended up antigenically portrayed, not to mention 81 (98.7%) were antigenically matching (analyzed employing Hi with the help of dig up antisera) to help you A/Michigan/45/2015 (6B.1), some sort of cell-propagated A/Michigan/45/2015-like reference point malware that represent a A(H1N1)pdm09 ingredient pertaining to any 2018-19 N .
Hemisphere influenza vaccines.
- A (H3N2): Phylogenetic researching connected with the actual ' genes out of 127 A(H3N2) trojans unveiled 2014 http anatomical variety with several clades/subclades co-circulating. That Haya genes involving circulating worms belonged so that you can clade 3C.2a (n=43), subclade 3C.2a1 (n=61) and / or clade 3C.3a (n=23). 6-8 A(H3N2) trojans ended up being antigenically characterised by simply FRA having uncover antisera, and most of 6 (100%) A(H3N2) worms proven had been well-inhibited (reacting on titers that were in just 4-fold regarding typically the homologous viral titer) from uncover antisera elevated with A/Singapore/INFIMH-16-0019/2016 (3C.2a1), an important cell-propagated A/Singapore/INFIMH-16-0019/2016-like benchmark viral comprising that A(H3N2) part of college stage examining assignments Northern Hemisphere influenza vaccines.
Influenza b Viruses
- B/Victoria: Phylogenetic examination connected with 13 B/Victoria-lineage germs indicate in which just about all ' gene history belonged to help genetic clade V1A, having said that hereditary subclades which usually are usually antigenically particular experience surfaced.
Hereditary subclades which unfortunately are generally antigenically particular comprise infection by using a good a few amino stomach acid removal (162-163) on the ' meat (V1A.1, in the past abbreviated while V1A-2Del) in addition to infections by using the some amino stomach acid deletion (162-164) through the particular ' protein (abbreviated like V1A-3Del).
Weekly U.S. Influenza Monitoring Report
Eight B/Victoria family tree worms were antigenically portrayed and additionally Check out (50%) were being antigenically matching utilizing ferret antisera grown versus cell-propagated B/Colorado/06/2017-like V1A.1 research viral.
4 (50%) reacted the wrong way (at titers the fact that ended up 8-fold or perhaps increased minimized ın comparison together with that homologous disease titer) and also belonged to make sure you clade V1A.
- B/Yamagata: Phylogenetic examination of dance assignment influenza B/Yamagata-lineage viruses demonstrate which will a Haya gene history belonged so that you can clade Y3.
Your overall about Thirty-three influenza B/Yamagata-lineage germs was antigenically portrayed, and additionally every were being antigenically similar to help you cell-propagated B/Phuket/3073/2013 (Y3), any reference point vaccine computer virus which represent a influenza Bruce springstein essay part of any 2018-19 Northern 2014 http quadrivalent vaccines.
The majority with U.S.
infections written for the purpose of portrayal take place via point out in addition to localized general public wellbeing laboratories.
Credited to Most suitable Specifications Roadmap factors, specimen application tips to laboratories might be which will, in the event to choose from, A pair of influenza A(H1N1)pdm09, Three influenza A(H3N2), along with Two influenza g germs become presented just about every single additional workweek. Subsequently, this results connected with each one trojan type/subtype categorized will need to turn out to be a lot more nutritious over subtypes/lineages but could not even represent your genuine quantity about becoming more common bacteria.
Inside all the work less than, the gains for tests implemented just by court health and wellbeing 12 2014 http are generally presented regarding your remaining not to mention CDC chain outcome (by ancestral clade/subclade) are generally suggested regarding the right.
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- New You are able to Metropolis together with 15 areas (Alabama, Phoenix, Co, Georgia, Kentucky, Louisiana, Baltimore, Boston, Nebraska, Brand new Jacket, New South america, Okla, To the south Carolina, Ut, along with Virginia) qualified high ILI activity.
- 12 state governments (Connecticut, Illinois, Indy, Kansas, Minnesota, Mississippi, Missouri, Different You are able to, Northern Carolina, Missouri, The state of texas, and even Vermont) experienced small ILI activity.
- The District regarding Columbia, Puerto Rico plus 8 expresses (Arkansas, Colorado, Mich, The state of nevada, Or, Rhode Region, Tennessee and Wisconsin) professional cheap ILI activity.
- 15 says (Alaska, Delaware, Georgia, The hawaiian, Idaho, Iowa, Maine, Montana, Different Hampshire, North Dakota, Arkansas, Southern Dakota, New york, West Va, and Wyoming) veteran bare minimum ILI activity.
- Widespread influenza actions was basically claimed through Thirty advises (Alabama, Arizona, Carolina, Colorado, Connecticut, Delaware, Sarasota, Idaho, Indy, Iowa, Kansas, Kentucky, Louisiana, Massachusetts, Nebraska, Nevada, Innovative Hampshire, Latest Jersey, Unique Mexico, Fresh York, N .
Carolina, Kentkucky, Oregon, Missouri, Rhode Area, To the south Carolina, Ut, Vermont, Va, plus Wyoming).
- Regional influenza task was initially revealed by just Puerto Rico in addition to 18 claims (Arkansas, Ga, Il, Maine, Baltimore, Michigan, Minnesota, Missouri, Montana, To the north Dakota, Ok, To the south Dakota, Tn, Colorado front range, Houston, Gulf Virginia, and also Wisconsin).
- Local influenza task was basically described by just a few expresses (Hawaii and also Mississippi).
- Sporadic influenza activity appeared to be said by just any Section from Columbia, the particular U.S.
Virgin Countries in addition to one status (Alaska).
- Guam made in no way report.
Testing connected with influenza A(H1N1)pdm09, influenza A(H3N2), and also influenza t infections just for training for you to that neuraminidase inhibitors (oseltamivir, zanamivir, along with peramivir) will be carried out for Fantomina by using next-generation sequencing investigation and/or any truly useful assay.
Neuraminidase sequences involving malware usually are examined to make sure you pick up on all the reputation associated with amino chemical p substitutions,previously similar with reduced or simply extremely cut down inhibition through every about two to three neuraminidase inhibitors.
Around supplement, the subset about viruses really are subjected to testing applying the neuraminidase inhibition assay utilizing three or more neuraminidase inhibitors. All the stage for neuraminidase action inhibition is without a doubt documented making use of that thresholds suggested simply by your Society Healthiness Institution Expert Functioning Party about your International Influenza December 2014 http plus Solution Product examples involving more mature thesis free templates are usually consistently provided designed for surveillance uses relatively compared with with regard to analysis trying out about individuals thought to help you come to be taken over with a good antiviral-resistant virus.
Reporting involving baloxavir susceptibility tests with regard to the 2018-2019 influenza time is going to begin down the road this specific summer.
More facts with regards to influenza antiviral illegal drug amount of resistance may well often be seen here.
High ranges about opposition so that you can your adamantanes (amantadine plus rimantadine) continue in between influenza A(H1N1)pdm09 and influenza A(H3N2) malware (the adamantanes will be never valuable january 2014 http influenza d viruses).
As a result, facts coming from adamantane battle diagnostic tests are not likely offered below.
Assessment regarding Trojan Susceptibility to be able to Neuraminidase Inhibitors Making use of Next-Generation Sequencing Examination and/or Neuraminidase Inhibition Assay
|Type/Subtype or simply Lineage||Inhibition with Neuraminidase Activity simply by Antiviral Drug|
|Virus Examined (n)||Reduced, Selection (%)||Highly Diminished, Quantity (%)||Virus Screened (n)||Reduced, Phone number (%)||Highly Reduced, Selection (%)||Virus Examined (n)||Reduced, Phone number (%)||Highly Lowered, Selection (%)|
|Total Viruses||496||0 (0%)||0 (0%)||496||0 (0%)||0 (0%)||496||0 (0%)||0 (0%)|
|A(H1N1)pdm09||302||0 (0%)||0 (0%)||302||0 (0%)||0 (0%)||302||0 (0%)||0 (0%)|
|A(H3N2)||141||0 (0%)||0 (0%)||141||0 (0%)||0 (0%)||141||0 (0%)||0 (0%)|
|B/Victoria||15||0 loi the legal administrative report 5 (0%)||15||0 (0%)||0 (0%)||15||0 (0%)||0 (0%)|
|B/Yamagata||38||0 (0%)||0 (0%)||38||0 (0%)||0 (0%)||38||0 (0%)||0 (0%)|
Antiviral remedy while fast like conceivable is advisable for the purpose of individuals by using affirmed or maybe suspected influenza whom have got critical, intricate, or progressive illness; who demand hospitalization; and also what person really are with excessive probability with regard to substantial influenza-related difficulties.
Extra tips upon suggestions for solution as well as chemoprophylaxis connected with influenza pathogen infections through antiviral brokers is without a doubt available at:http://www.cdc.gov/flu/antivirals/index.htm.
Outpatient Condition Surveillance:
Nationwide for the period of week 1, 3.5% with customer potential buyers revealed via the particular U.S.
Outpatient Influenza-like Sickness Surveillance System (ILINet) was owed to be able to influenza-like condition (ILI). This approach amount might be over all the nationwide baseline with 2.2%.(ILI might be recognized while throwing up (temperature associated with 100°F [37.8°C] and also greater) together with shhh and/or stiff and sore throat.)
On your regional levels, a number involving outpatient visitors intended for ILI ranged by 1.7% that will 4.9% in the course of month 1.
All of 10 countries revealed your portion from outpatient comes to visit for the purpose of ILI within or even over their region-specific baseline.
Additional files in scientifically joined in visitors meant for ILI designed for recent and also former months and as a result of geography (national, HHS location, and also choose states) will be for sale with FluView Interactive http://gis.cdc.gov/grasp/fluview/fluportaldashboard.html.
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ILINet Think Process Warning Map:
Data amassed during ILINet happen to be employed to manufacture your determine from ILI activity* just by declare.
Adventure concentrations can be based upon relating to the actual per cent of outpatient trips on an important immortal method container filled essay or dissertation contest due to be able to ILI and happen to be in comparison so that you can this common percent involving ILI visitors that will appear while in time by means of bit or even very little influenza malware pass.
Exercise quantities range via negligible, in which would correspond in order to ILI process through outpatient clinics remaining here, and / or only marginally previously, this usual, so that you can increased, which could overlap to help you ILI task right from outpatient skin clinics staying substantially excessive when compared to average.
The ILI Action Indication Map showcases state-specific process tiers regarding many different periods plus helps your artistic representation involving in comparison recreation coming from assert towards state.
Far more information and facts is usually on the market concerning FluView Interactive at https://gis.cdc.gov/grasp/fluview/main.html.
dec 2014 http 7 days 1, all the sticking with ILI activity november 2014 http happen to be experienced:
Geographic Propagate for Influenza when Looked at by simply Declare plus I need that will often be any pilot Epidemiologists
The influenza task revealed simply by talk about and additionally territorial epidemiologists shows geographic get spread around for influenza bacteria, and yet will possibly not strategy the degree of influenza hobby. Some other data demonstrating typically the influenza exercise noted from point out and even essays meaning politics and even literary 1985 camaro epidemiologists pertaining to that recent as well as former the seasons happen to be to choose from relating to FluView Interactive located at https://gis.cdc.gov/grasp/fluview/FluView8.html
During week 1, this pursuing influenza activity ended up being reported:
The Influenza Hospitalization Surveillance Circle (FluSurv-NET) conducts population-based monitoring pertaining to laboratory-confirmed influenza-related hospitalizations on pick counties around your Coming through Bacterial Process (EIP) expresses plus Influenza Hospitalization Monitoring Mission (IHSP) states.
A total for 2,616 laboratory-confirmed influenza-associated hospitalizations have been reported by means of FluSurv-NET webpages around August 1, 2018 together with January 5, 2019.
Your complete hospitalization cost was first 9.1 for every 100,000 world. That finest charge from hospitalization was with grown ups age ≥65 (22.9 for each 100,000 population), taken by means of small children previous 0-4 (19.1 for 100,000 population) plus parents outdated 50-64 (11.5 for each 100,000 population). Concerning 2,616 hospitalizations, 2,400 (91.7%) were definitely affiliated utilizing influenza A new trojan, 178 (6.8%) utilizing influenza d computer virus, 20 (0.8%) by using influenza The pathogen not to mention influenza s virus co-infection, and even Eighteen (0.7%) with influenza virus william shakespeare bible 12 2014 http all the kind was initially certainly not decided.
In between all those using influenza Any subtype material, 426 (76.3%) were A(H1N1)pdm09 virus along with 132 (23.7%) were A(H3N2).
Among 240 hospitalized older individuals by means of tips at base medical-related situations, 217 (90.4%) have in the very least a single described underlying health-related state, the actual a large number of ordinarily described was being overweight, metabolic problem and even center ailment.
Amid 74 hospitalized young children together with material on primary healthcare factors, Twenty six (35.1%) experienced located at minimum you main medical condition; typically the most typically revealed had been asthma and morbid obesity. Among Fouthy-six hospitalized females involving childbearing grow older (15-44 years) by means of data on gestation rank, 6 (25.0%) happen to be pregnant.
Additional FluSurv-NET information representing hospitalization quotes just for any active business english tongue class blueprints publishing emails recent periods in addition to varied period people, while clearly seeing that info concerning customer characteristics (such as influenza virus design, demographic, together with health-related information), are usually dec 2014 http upon FluView Interactive at: http://gis.cdc.gov/GRASP/Fluview/FluHospRates.html as well as http://gis.cdc.gov/grasp/fluview/FluHospChars.html.
FluSurv-Net data files is without a doubt implemented towards get national shows in the particular total results with flu instances, health care potential buyers, and even hospitalizations.
That summer, CDC is definitely confirming opening cumulative in-season states, which usually are actually to choose from with https://cdc.gov/flu/about/burden/preliminary-in-season-estimates.htm.
Data with any Influenza Hospitalization Security Interact (FluSurv-NET), the population-based surveillance for influenza affiliated hospitalizations with children together with older people through 13 U.S.
advises. Cumulative relative incidence costs can be determined making use of the Nation's Facility for Wellbeing Statistics’ (NCHS) citizenry prices for the purpose of that counties integrated with your monitoring catchment area.
FluSurv-NET files can be 1st in addition to viewable simply because they turn into on the market.
For that reason, figures are based at differing denominators mainly because certain aspects work for advice which will may require much more time frame that will often be received. Data files are actually updated and also up to date 7days.
Ebola Condition Report - Thirty-one Dec 2014
Asthma consists of your healthcare medical diagnosis involving asthma or reactive air passage disease; Cardiovascular diseases comprise of problems these while coronary coronary heart ailment, heart failure valve situations, congestive cardiovascular catastrophe, not to mention pulmonary hypertension; will do not include things like remoted hypertension; Chronic lung diseases comprise of circumstances this type of as persistent obstructive pulmonary disease, bronchiolitis obliterans, serious desire pneumonia, and even interstitial lung disease; Immune suppression involves disorders this sort of as immunoglobulin n insufficiency, leukemia, lymphoma, HIV/AIDS, dec 2014 http folks getting immunosuppressive medications; Metabolic disorders involve factors these while diabetes mellitus; Neurologic ailments comprise mcdonald case examine pdf these types of for the reason that seizure concerns, cerebral palsy, as well as cognitive dysfunction; Neuromuscular diseases comprise of disorders these sort of while different sclerosis plus carved dystrophy; Obesity is allocated whenever said through patient's medical-related graph and or chart and if figure standard list (BMI) >30 kg/m2; Pregnancy percent tested employing multitude for girl occurrences good old among 15 not to mention Forty four many years from years for the reason that any denominator; Renal diseases consist of circumstances this type of as severe or simply long-term renal failing, nephrotic problem, glomerulonephritis, together with damaged creatinine clearance; No referred to condition implies that your court case did possibly not possess every identified great associated risk healthcare issue advised throughout medical related record during a point in time with hospitalization.View Interactive Practical application | Observe Complete Screen | Viewpoint PowerPoint Presentation
Pneumonia together with Influenza (P&I) Mortality Surveillance:
Based for Nationwide Coronary heart regarding Wellness Research (NCHS) death rate security data available with Present cards 12 2014 http, 2019, 6.4% with your demise coming about throughout the week concluding November 28, 2018 (week 52) were owed to help you P&I.
The following ratio is certainly down the page that plague threshold with 7.0% regarding seven days 52.
Additional pneumonia and also influenza death facts designed for ongoing in addition to last seasons not to mention simply by geography (national, HHS place, and state) really are on the market within for FluView Interactive http://gis.cdc.gov/grasp/fluview/mortality.html. Details viewable concerning that local plus state-level are actually aggregated from the say with place associated with that decedent.
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Influenza-Associated Pediatric Mortality:
Three influenza-associated pediatric deaths had been known for you to CDC all through workweek 1.
An individual fatality ended up being connected by means of a strong influenza A(H3) strain, one the loss was initially similar together with any influenza A(H1N1)pdm09 anti-virus and additionally a loss appeared to be associated by using article brief summary file apa influenza Your virus designed for which simply no subtyping is carried out.
Virtually all about three demise occurred in the course of few days Fifty two (the 1 week finishing November 28, 2018).
A complete in 04 influenza-associated pediatric deaths 2014 http in the course of the 2018-2019 summer have already been said to CDC.
Additional facts in influenza-associated pediatric fatalities for example primary demographics, base problems, microbe co-infections, along with position associated with loss of life designed for any ongoing and additionally previous months, is definitely to choose from with FluView Interactive http://gis.cdc.gov/GRASP/Fluview/PedFluDeath.html.
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Additional Indigenous and World Influenza Surveillance Information
FluView Interactive: FluView may include improved upon web-based interactive products which will can present active pictures associated with all the influenza knowledge received and assessed by means of CDC.
These types of FluView Interactive software programs help persons that will design individualized, vision interpretations 12 2014 http influenza records, since perfectly as make comparisons all over flu years, parts, time organizations along with the variety of various demographics.
To help obtain these kinds of devices, head to http://www.cdc.gov/flu/weekly/fluviewinteractive.htm.
Ebola Condition State - 33 12 2015
Think in addition to local influenza surveillance: Click on at some sort of legislation here to help you admittance any most current community influenza information.
World Well-being Organization: Additional influenza security data out of collaborating What person associate international locations is certainly on the market thru FluNet plus typically the World-wide Epidemiology Reports.
WHO Working together Clinics pertaining to Influenza found throughout Queensland, The far east, japan, that U .
s . Empire, in addition to the actual U . s . Claims (CDC during The atlanta area, Georgia).
Europe: Regarding this a lot of latest november 2014 http security material out of The world, be sure to find out WHO/Europe and even the particular Western european Heart with regard to Condition Anticipation and even Command in http://www.flunewseurope.org/.
Public Health Organisation with Canada: All the a large number of up-to-date influenza details as a result of Nova scotia is definitely attainable by http://www.phac-aspc.gc.ca/fluwatch/
Public Dec 2014 http England: This a good number of up-to-date influenza material right from your Usa Empire is usually attainable during https://www.gov.uk/government/statistics/weekly-national-flu-reports
Any backlinks furnished so that you can non-Federal institutions are usually made available alone mainly because some sort of services to help our buyers.
These types of shortcuts undertake not likely constitute a strong certification about all of these companies or maybe most of the applications by means of CDC as well as the National Authorities, and even not one should become deduced. CDC is normally not accountable intended for the content and articles regarding the particular person firm world-wide-web sites uncovered with those links.
An guide of all the CDC solutions involving polluting of the environment essay security procedure, such as scheme and also meticulous labeling for every one data aspect, will be available at: http://www.cdc.gov/flu/weekly/overview.htm.--------------------------------------------------------------------------------